Sfoglia per Soggetto "Endocrinology"
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Functional cooperation between GPER and AHR toward breast cancer progression
(2019-04-11)The cytochrome P450 1B1 (CYP1B1) is a heme-thiolate monooxygenase involved in both estrogen and environmental contaminants metabolism. For instance, CYP1B1 catalyzes the hydroxylation of 17-β estradiol (E2) leading to ... -
Role of ERalpha/NOTCH4 axis in sustaining stemness in breast cancer cells
(2018-02-27)Early detection and new therapeutic strategies have improved breast cancer patient outcome and survival rates in the last years. However, breast cancer still remains the second leading cause of cancer-related deaths among ...