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Development and optimization of analytical protocols based on microextraction techniques for clinical screening and environmental control
(2019-03-21)
The development of analytical protocols for the determination of analytes at trace levels in complex matrices (e.g. biological fluids or contaminated water) is a crucial point for the environmental assessment and monitoring ...
Transition metal-based complexes as chemitherapeutic agents. Theoretical investigation of MoA, interaction with biological molecules and environmental conditions
(2017-05-05)
Molti metalli e, conseguentemente, molti complessi metallici svolgono ruoli importanti all’interno di sistemi biologici e biochimici. Oggigiorno, è risaputo che essi rappresentano ingredienti molto importanti per la vita ...
Computational study of new drugs for photodynamic therapy
(2017-05-05)
Photodynamic'therapy'(PDT)'is'a'non:invasive'therapeutic'technique'
for' the' treatment' of' different' kind' of' tumours' through' the' production' of'
reactive'oxygen'species'(ROS)'that'act'as'cytotoxic'agents.''''
PDT'works' ...
Eco-friendly extraction of bioactive compounds from olive (drupes and leaves), Stevia and Schizochytrium sp.
(2017-04-13)
The use of nutraceutical compounds, as well as their extraction from natural sources, is
now the subject of studies in various sectors.
The research groups working in this field focus their attention on the optimization ...
Advanced mass spectrometric approaches for the determination of food quality and development of new methodologies for enrichment of nutraceuticals in functional foods
(2018-02-27)
The research works presented in this Ph.D. thesis are based on the nutraceuticals and functional foods research.
The first part of the thesis deals with three main topics:
1. Structural characterization of new HMG-flavonoids ...
A computational mechanistic study of potentially evolving platinum based anticancer drugs
(Università della Calabria, 2021)
Metals are known to play a fundamental physiological role inside human
body affecting many of the biological functions. Analogously, metal based
drugs can also have a similar impact. Cisplatin, a simple platinum complex,
is ...