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Items 11-20 di 29
Role of PPARy in the complex interplay between brest cancer cells and tumor microenvironment
(2019-03-21)
Stromal Derived Factor-1α (SDF-1α) and its cognate receptor CXCR4 play a key role in
mediating breast cancer cell invasion and metastasis. Therefore, drugs able to inhibit
CXCR4 activation may add critical tools to reduce ...
Benefits of advanced techniques and data processing for the analysis of complex biological and food matrices
(2019-03-03)
Durante i tre anni di dottorato in Medicina Traslazionale, il mio lavoro di ricerca si è concentrato sull'applicazione di tecniche analitiche avanzate e sull'elaborazione dei dati per lo studio di matrici complesse biologiche ...
Estrogen receptor alpha interferes with LKBl/AMPK/mTOR signaling activation in adiponectin-treated breast cancer cells
(2018-02-27)
Breast cancer is the most common type of tumor and the leading cause of
cancer-related deaths in women, worldwide. The cause of breast cancer is
multifactorial and includes hormonal, genetic and environmental cues. Obesity ...
Transition metal-based complexes as chemitherapeutic agents. Theoretical investigation of MoA, interaction with biological molecules and environmental conditions
(2017-05-05)
Molti metalli e, conseguentemente, molti complessi metallici svolgono ruoli importanti all’interno di sistemi biologici e biochimici. Oggigiorno, è risaputo che essi rappresentano ingredienti molto importanti per la vita ...
Computational study of new drugs for photodynamic therapy
(2017-05-05)
Photodynamic'therapy'(PDT)'is'a'non:invasive'therapeutic'technique'
for' the' treatment' of' different' kind' of' tumours' through' the' production' of'
reactive'oxygen'species'(ROS)'that'act'as'cytotoxic'agents.''''
PDT'works' ...
Eco-friendly extraction of bioactive compounds from olive (drupes and leaves), Stevia and Schizochytrium sp.
(2017-04-13)
The use of nutraceutical compounds, as well as their extraction from natural sources, is
now the subject of studies in various sectors.
The research groups working in this field focus their attention on the optimization ...
FoxO3a reactivation restores the sensitivity to the antiestrogen treatment in tamoxifen resistant breast cancer
(2017-06-12)
Resistance to endocrine treatments is a major clinical challenge in the management of estrogen
receptor alpha positive (ER+) breast cancers (BC). Although multiple mechanisms leading to
endocrine resistance have been ...
Study of antimicrobial and anticancer activity of new synthetic and natural tools
(2017-06-12)
Infectious diseases and cancer are the two disease groups that representing the major
cause of death worldwide. Unfortunately, antibiotic resistance is the biggest threat in the first
case; in fact, new resistance ...