Sfoglia Dipartimento di Farmacia e Scienze della Salute e della Nutrizione - Tesi di Dottorato per Titolo
Items 61-80 di 103
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Mechanisms of RA action in steroidogenic tissues and pro-apoptotic effects of combined treatment of breast tumoral cell lines with 9-cis retinoic acid and rosiglitazione
(2008-11-20)Vitamin A (Retinol) plays a central role in many essential biological processes such as vision, immunity, reproduction, growth, development, control of cellular proliferation and differentiation. The main active forms ... -
Modelli sperimentali cellulari e molecolari per la valutazione della tossicità di xenobiotici
(2013-12-02)The aim of my thesis was to find two different experimental models to study cellular and molecular xenobiotics toxicity. In the first part of the present work we studied the interaction between two different plasma ... -
New natural statin-like compounds with anticholesterolemic and antiproliferative properties: "in vitro and in vivo studies"
(2015-12-18)Il rischio di malattia coronaria è aumentato negli individui che mostrano elevata concentrazione di colesterolo nelle lipoproteine plasmatiche a bassa densità (LDL). E’ stato dimostrato che l’inibizione del 3-idrossi-3 ... -
Novel molecular mechanisms involved in the stimulatory action of zinc in breast cancer
(2016-11-22)Lo Zinco (Zn), minerale essenziale che regola diverse funzioni biologiche, è coinvolto nella progressione del tumore mammario. In particolare, è stato dimostrato che in seguito all’attivazione indotta dallo Zn di recettori ... -
Nuove strategie sperimentali per la comprensione e il trattamento dell’ischemia cerebrale
(2011-11-28)Ischemic stroke is a leading cause of death and long-term disabilities worldwide. Although the pathophysiology of stroke has been studied extensively and several drugs have been proposed in preclinical trials, the ... -
PELP1, EGR-1 and ERRα as potential targets for new therapies against adrenocortical carcinoma
(2019-07-30)I Carcinomi surrenalici (ACC) sono tumori rari e altamente aggressivi, associati a una prognosi molto sfavorevole, principalmente a causa di un alto rischio di recidiva e di opzioni terapeutiche limitate (Stojadinovic ... -
Polymer-based drug delivery systems: a study on micro and nanoparticles as carriers for bioactive molecules
(2019-04-18)The works presented in this book are the result of the research carried out by the candidate, Luca Scrivano, during his 3 years Ph.D. at the Department of Pharmacy, Health and Nutritional Sciences of the University of ...