Sfoglia Dipartimento di Farmacia e Scienze della Salute e della Nutrizione - Tesi di Dottorato per Autore "Bonofiglio, Daniela"
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Dynamic effects of retinoic acid and its isomers on cancer and physiology
Perri, Mariarita; Bonofiglio, Daniela; Sisci, Diego (2010-11-23)In the search for new cancer chemo-preventive compounds, hundreds of naturally occurring molecules have been evaluated. Among these, antioxidants appear to be very promising. In this contest, over the last decade retinoids, ... -
Mechanisms of RA action in steroidogenic tissues and pro-apoptotic effects of combined treatment of breast tumoral cell lines with 9-cis retinoic acid and rosiglitazione
Pingitore, Attilio; Bonofiglio, Daniela; Sisci, Diego (2008-11-20)Vitamin A (Retinol) plays a central role in many essential biological processes such as vision, immunity, reproduction, growth, development, control of cellular proliferation and differentiation. The main active forms ... -
Molecular mechanism of PPARγ mediated apoptosis in different cancer celles
Qi, Hongyan; Sisci, Diego; Bonofiglio, Daniela (2008-11-26) -
PPARγ ligands as novel agents able to inhibit breast tumor growth and progression
Vizza, Donatella; Sisci, Diego; Bonofiglio, Daniela (2011) -
Role of PPAR γ in breast cancer cell death and in adipocyte differentiation
Rovito, Daniela; Sisci, Diego; Bonofiglio, Daniela (2013-12-02) -
Role of PPARy in the complex interplay between brest cancer cells and tumor microenvironment
Gionfriddo, Giulia; Andò, Sebastiano; Bonofiglio, Daniela (2019-03-21)Stromal Derived Factor-1α (SDF-1α) and its cognate receptor CXCR4 play a key role in mediating breast cancer cell invasion and metastasis. Therefore, drugs able to inhibit CXCR4 activation may add critical tools to reduce ... -
Stromal cells in breast cancer microenvironment: molecular mechanisms involved in tumor progression and potential therapeutic targets
Augimeri, Giuseppina; Andò, Sebastiano; Bonofiglio, Daniela; Kleer, Celina (Università della Calabria, 2021-03-26)Stromal cells in the tumor microenvironment (TME) play an important role in breast cancer progression, metastasis and therapeutic outcome. Among stromal cells, Tumor-Associated Macrophages (TAMs) and Mesenchymal Stem Cells ...