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Effects of erythropoietin and stem cell factor on normal and cancer cells: implication for supportive therapy in oncological patients
(2013-10-23)
The ability of erythropoietin (Epo) to promote the production of red cells is currently exploited to
treat chemotherapy-induced anemia. However, the expression of Epo receptor (EpoR) in a variety
of cancer cells suggests ...
Ruolo del sistema endocannabinoide nei meccanismi di neuroprotezione da 17β-estradiolo in un modello sperimentale di ischemia cerebrale focale
(2013-10-28)
In questo studio sono stati determinati i livelli endogeni dell’endocannabinoide finora
meglio caratterizzato, anandamide (AEA) e l’attività degli enzimi responsabili,
rispettivamente, della sua sintesi e degradazione, ...
Dynamic effects of retinoic acid and its isomers on cancer and physiology
(2010-11-23)
In the search for new cancer chemo-preventive compounds, hundreds of naturally
occurring molecules have been evaluated. Among these, antioxidants appear to be
very promising. In this contest, over the last decade retinoids, ...
Mechanisms of RA action in steroidogenic tissues and pro-apoptotic effects of combined treatment of breast tumoral cell lines with 9-cis retinoic acid and rosiglitazione
(2008-11-20)
Vitamin A (Retinol) plays a central role in many essential biological processes such as
vision, immunity, reproduction, growth, development, control of cellular proliferation and
differentiation. The main active forms ...