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Estrogen Receptor beta, through Sp1, recruits a corepressor complex to the Estrogen Receptor alpha gene promoter in breast cancer cells
(2012)
Human Estrogen receptors alpha (α) and beta (β) are essential components of a
complex signal transduction pathway that regulates mammary growth and
development. Several studies have reported that normal breast tissues ...
Bisphenol A induces gene expression changes an proliferative effects through GPER in breast cancer celles and cancer-associated fibroblasts
(2012)
Bisphenol A (BPA) is the principal constituent of baby bottles, reusable water bottles,
metal cans, and plastic food containers. BPA exerts estrogen-like activity by interacting
with the classical estrogen receptors (ER ...
Effetti dell'olio essenziale di Bergamotto (Citrus bergamia Risso et poiteau) su processo autofagico: identificazione dei meccanismi coinvolti e dei componenti responsabili
(2012)
Nel presente studio, condotto in vitro, è stato valutato il coinvolgimento del processo autofagico
negli effetti biologici dell’olio essenziale di bergamotto, BEO (Citrus Bergamia, Risso et Poiteau),
un fitocomplesso ...
GPER mediates the up-regulation of acid synthase (fasn) intuced by 17B-estradiol in cancer cell and in cancer-associated fibroblasts (CAFs)
(2012-11-26)
Activation of lipid metabolism is an early event in carcinogenesis and a central hallmark of
many tumors. Fatty acid synthase (FASN) is a key lipogenic enzyme catalyzing the terminal
steps in the de novo biogenesis of ...