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Design, synthesis and characterization of suitable nitrones for several synthetic applications
(2013-11-21)
The present work takes advance of nitrone chemistry
flexibility in order to synthesize, on one hand, bisphosphonates
containing N,O-carbocyclic nucleoside units with potential biological
activity, starting from nitrones ...
Development and optimization by experimental design of solid phase microextraction gas chromatography triple quadrupole mass spectrometry methods in aqueous matrices
(2012-11-30)
Il presente lavoro di tesi relativo all‘attività di ricerca svolta durante il triennio di dottorato ha riguardato la messa a punto di metodi analitici per la determinazione di analiti in due distinte aree di interesse. La ...
Advanced mass spectrometry-based strategies for the isolation and characterization of G protein-coupled estrogen receptor 1(GPR)
(2014-11-28)
Estrogen signaling plays a vital role in breast, ovarian and endometrial cancers.
The actions of estrogen are mainly mediated by classical estrogen receptors, ERα and
ERβ that belongs to the nuclear receptor superfamily. ...