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Novel molecular mechanisms involved in the stimulatory action of zinc in breast cancer
(2016-11-22)
Lo Zinco (Zn), minerale essenziale che regola diverse funzioni biologiche, è coinvolto nella
progressione del tumore mammario. In particolare, è stato dimostrato che in seguito all’attivazione
indotta dallo Zn di recettori ...
Bisphenol A induces gene expression changes an proliferative effects through GPER in breast cancer celles and cancer-associated fibroblasts
(2012)
Bisphenol A (BPA) is the principal constituent of baby bottles, reusable water bottles,
metal cans, and plastic food containers. BPA exerts estrogen-like activity by interacting
with the classical estrogen receptors (ER ...
GPER mediates the up-regulation of acid synthase (fasn) intuced by 17B-estradiol in cancer cell and in cancer-associated fibroblasts (CAFs)
(2012-11-26)
Activation of lipid metabolism is an early event in carcinogenesis and a central hallmark of
many tumors. Fatty acid synthase (FASN) is a key lipogenic enzyme catalyzing the terminal
steps in the de novo biogenesis of ...