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Towards more sustainable organic processes : heterocyclizations in non-conventional solvents
(2017-09-19)
This thesis reports the synthesis of important heterocyclic derivatives by iodocyclization, carbonylation and cycloisomerization reactions in Non-Conventionl solvents like deep eutectic solvents (DES) and Ionic Liquids ...
Advanced mass spectrometry-based strategies for the isolation and characterization of G protein-coupled estrogen receptor 1(GPR)
(2014-11-28)
Estrogen signaling plays a vital role in breast, ovarian and endometrial cancers.
The actions of estrogen are mainly mediated by classical estrogen receptors, ERα and
ERβ that belongs to the nuclear receptor superfamily. ...
Different medicinal chemistry approaches towards the identification of novel targets in breast cancer
(2013-12-02)
G protein-coupled receptors (GPCRs) belong to the largest family of cellsurface
molecules representing the targets of approximately 40% of
current medicinal drugs (Overington, J.P et al 2006). GPCRs are
ubiquitous in ...
Innovative fluorinated membranes for water and organic solvent treatment application
(2017-09-19)
The aim of this thesis was to study the use of different types of fluoropolymer in order to prepare membranes for chemical and pharmaceutical applications. In fact, the potential use of fluoropolymeric membranes respect ...