• Contribution of flavonoids and iridoids to health properties of edible plants of Arbutas, Cornas, and Vuccinium genera from Mediterranean area 

  Tenuta, Maria Concetta; Tundis, Rosa; Andò, Sebastiano; Deguin, Brigitte; Lallemand, Marie-Christine (Università della Calabria, 2020-06-19)

  Aim of the study: Natural compounds produced by the “nature laboratory” continue to play a leading role in the process of discovering and developing of new drugs, food supplements and/or functional foods. Today, in fact, ...

• Effect of bergamot essential oil and its constituent linalool on myogenic and neuronally-mediated contractions of human and rat isolated colon: potential benefits in complementary treatment of intestinal diseases 

  Straface, Marilisa; Andò, Sebastiano; Morrone, Luigi (Università della Calabria, 2020-07-01)

  Introduction Bergamot essential oil (BEO) is used in aromatherapy and as an additive to food and drink to promote a citrus flavour. In animal models, BEO can modulate the synaptic functions within the Central Nervous ...

• Evaluation of a PH-sensitive mesoporous silca -based nanosystem as a vehicle for targetedcancer therapy 

  Nigro, Alessandra; Andò, Sebastiano; Sisci, Diego (Università della Calabria, 2020-04-17)

• Advanced and smart nanocarriers for pharmaceutical applications 

  Mazzotta, Elisabetta; Andò, Sebastiano; Muzzalupo, Rita (Università della Calabria, 2020-04-17)

  The application of nanotechnology in drug formulation has made significant headway over the last decade. Nanoscale controlled release systems allow to revalue and reformulate old drugs through targeted delivery to the ...

• New perspective for the use of citrus by-productus in food and nutraceutical industries 

  Leporini, Mariarosaria; Andò, Sebastiano; Loizzo, Monica Rosa (Università della Calabria, 2020-07-06)

  Aim of the study: Citrus is the most produced tree fruit crop in the world. Almost 33% of the Citrus fruits are industrially processed for juice production, however, a great amount of Citrus wastes including peels, segment ...

• Synthetic strategies towards short-chain peptides for potential biomedical applications and tumor-targeted mesoporous silica-based drug delivery systems development 

  Comandè, Alessandra; Andò, Sebastiano; Leggio, Antonella (Università della Calabria, 2020-04-17)

  My PhD research project was focused on the design and development of short-chain peptides with biomedical applications and on the identification of new peptide synthesis strategies. Briefly, the specific objectives of my ...

• Novel insight into the protective role of androgen receptor in ER-positive breast cancer 

  Chiodo, Chiara; Andò, Sebastiano; Lanzino, Marilena (Università della Calabria, 2020-04-17)

  Introduction: Androgen receptor (AR) role in breast cancer appears to be clinically relevant and disease context specific. In estrogen receptor (ER) α-positive primary breast cancers, AR positivity correlates with low tumor ...

• Chemical modifications of polyphenols for the development of new molecules foods for the treatment of metabolic disorders 

  Carullo, Gabriele; Andò, Sebastiano; Aiello, Francesca (Università della Calabria, 2020-07-01)

  Metabolic disorders represent the principal cause of death in the industrialized world, affecting several people, because of their incorrect lifestyle. Among them, Type 2 Diabetes Mellitus and related comorbidities, such ...

• Advanced functionalized materials for multipurpose applications 

  Pantuso, Elvira; Andò, Sebastiano; Nicoletta, Fiore (Università della Calabria, 2021-03-21)

• Sistemi polimerici multicomponente per la veicolazione di principi attivi 

  Farfalla, Annafranca; Andò, Sebastiano; Iemma, Francesca (Università della Calabria, 2021-02-25)

  L’attività di ricerca riportata nel presente lavoro di tesi di dottorato si inserisce nel contesto della sintesi e caratterizzazione di materiali multifunzionali per la veicolazione e il direzionamento di principi ...

• Evidence that ANG II/AGTR1 signaling stimulates aromatase activity, enhances local estrogen production involved in Glioblastoma cell growth and progression 

  Russo, umberto; Andò, Sebastiano; De Amicis, Francesca (Università della Calabria, 2021-04-01)

• Progesterone Receptor B disrupts the metabolic reprogramming in breast cancer cell lines producing death by blocking energy producing pathways, and p53 may be linked in this tumour suppressive-action 

  Santoro, Marta; Andò, Sebastiano; Aquila, Saveria (Università della Calabria, 2021-11-10)

  Il carcinoma mammario (BC) rappresenta la più comune causa di morte per neoplasia nella donna. Nonostante i progressi fatti nella diagnosi precoce e nella terapia, esso resta una delle forme tumorali con prognosi infausta. ...

• Application of computational methodologies toward the identification of novel therapeutics and photodegradation studies for the design of light-stable formulations 

  Occhiuzzi, Maria Antonietta; Andò, Sebastiano; Grande, Fedora; Iole, Giuseppina (Università della Calabria, 2021-06-10)

• Charatterization of store-operated calcium entry in the neuroimmune response evoked by ischemic preconditioning in mice subjected to middle cerebral artery occlusion 

  Frisina, Marialaura; Andò, Sebastiano; Amantea, Diana (Università della Calabria, 2021-06-10)

  Cerebral ischemia is one of the leading causes of death and long-term disability worldwide. Currently approved therapies for ischemic stroke are limited to reperfusion through mechanical recanalization and/or pharmacological ...

• Stromal cells in breast cancer microenvironment: molecular mechanisms involved in tumor progression and potential therapeutic targets 

  Augimeri, Giuseppina; Andò, Sebastiano; Bonofiglio, Daniela; Kleer, Celina (Università della Calabria, 2021-03-26)

  Stromal cells in the tumor microenvironment (TME) play an important role in breast cancer progression, metastasis and therapeutic outcome. Among stromal cells, Tumor-Associated Macrophages (TAMs) and Mesenchymal Stem Cells ...

• GPER mediates the up-regulation of acid synthase (fasn) intuced by 17B-estradiol in cancer cell and in cancer-associated fibroblasts (CAFs) 

  Santolla, Maria Francesca; Maggiolini, Marcello; Sisci, Diego (2012-11-26)

  Activation of lipid metabolism is an early event in carcinogenesis and a central hallmark of many tumors. Fatty acid synthase (FASN) is a key lipogenic enzyme catalyzing the terminal steps in the de novo biogenesis of ...

• FoxO3a reactivation restores the sensitivity to the antiestrogen treatment in tamoxifen resistant breast cancer 

  Donà, Ada Alice; Andò, Sebastiano; Sisci, Diego (2017-06-12)

  Resistance to endocrine treatments is a major clinical challenge in the management of estrogen receptor alpha positive (ER+) breast cancers (BC). Although multiple mechanisms leading to endocrine resistance have been ...

• Activated FXR inhibits leptin signaling and counteracts tumor-promoting activities of cancer-associated fibroblasts in breast malignancy 

  Vircillo, Valentina; Andò, Sebastiano; Catalano, Stefania (2017-06-12)

  Cancer-associated fibroblasts (CAFs), the principal components of the tumor stroma, play a central role in cancer development and progression. As an important regulator of the crosstalk between breast cancer cells and CAFs, ...

• Stimulatory actions of IGF-I are mediated by IGF-IR cross-talk with GPER and DDR1 in mesothelioma and lung cancer cells 

  Avino, Silvia; Andò, Sebastiano; Maggiolini, Marcello (2017-06-12)

  Insulin-like growth factor-I (IGF-I)/IGF-I receptor (IGF-IR) system has been largely involved in the pathogenesis and development of various tumors. We have previously demonstrated that IGF-IR cooperates with the G-protein ...

• Idrogel funzionali per la veicolazione di principi attivi 

  Spataro, Tania; Andò, Sebastiano; Picci, Nevio (2017-06-12)

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