Dipartimento di Farmacia e Scienze della Salute e della Nutrizione - Tesi di Dottorato: Recent submissions
Items 81-100 di 106
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Ruolo di iASPP nella regolazione del Mismatch repair in melanoma
(2014-05-22)Cutaneous melanoma is an aggressive malignancy accounting for 4% of skin cancers but 80% of all skin-cancer related deaths. Its incidence is rapidly rising and advanced disease is notoriously treatment-resistant. The role ... -
Caratterizzazione del profilo neurochimico, neuropatologico e neourofarmacologico di un modello sperimentale di glaucoma acuto
(2013-10-28)Glaucoma is a leading cause of irreversibile blindness characterized by the progressive loss of retinal ganglion cells (RGCs). Elevated intraocular pressure is a major risk factor for glaucoma; however, medical therapies ... -
Ruolo del sistema endocannabinoide nei meccanismi di neuroprotezione da 17β-estradiolo in un modello sperimentale di ischemia cerebrale focale
(2013-10-28)In questo studio sono stati determinati i livelli endogeni dell’endocannabinoide finora meglio caratterizzato, anandamide (AEA) e l’attività degli enzimi responsabili, rispettivamente, della sua sintesi e degradazione, ... -
Effects of erythropoietin and stem cell factor on normal and cancer cells: implication for supportive therapy in oncological patients
(2013-10-23)The ability of erythropoietin (Epo) to promote the production of red cells is currently exploited to treat chemotherapy-induced anemia. However, the expression of Epo receptor (EpoR) in a variety of cancer cells suggests ... -
Relevance of nuclear IRS-1 in breast cancer
(2013-10-23)Insulin receptor substrate 1 (IRS-1), one of the major molecules transmitting signals from the insulin and insulin-like growth factor 1 receptors, has been implicated in breast cancer. Recently, data obtained in different ...