Browsing Dipartimento di Biologia, Ecologia e Scienze della Terra - Tesi di dottorato by Title
Now showing items 73-92 of 190
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I nitriti come molecola segnale: effetti diretti e indiretti sulla regolazione dell'attività cardiaca
(2012-11-20)Nitrite anion is a physiological NO storage form and an alternative way for NO generation, recently emerged as a cardioprotective endogenous modulator. Using Langendorff perfused rat hearts, as paradigms of mammals heart, ... -
<<I>> sintomi comportamentali e psicologici nella malattia di Alzheimer: esordio e differenze di genere
(2018-05-11)BPSD have a deep physical and psychological impact on patients affected by any kind of dementing illness and on caregiver in terms of costs and resources and represent an important cause of institutionalization. The aim ... -
<<Ia>> catestatina migliora la risposta Frank-Starling in cuori di ratto normotesi e ipertesi agendo come attivatore fisiologico del pathway trasduzionale ossido nitrico-dipendente
(16-12-2015)The myocardial response to mechanical stretch (Frank-Starling law) is an important physiological cardiac determinant. Modulated by many endogenous substances, it is impaired in the presence of cardiovascular pathologies ... -
Identification of a feral olive dehydrin gene and its development as a tool for drought tolerance in Arabidopsis thaliana
(2013-11-28)Stress abiotici, quali deficit idrico e salinizzazione del suolo influenzano negativamente la crescita delle piante e la produttività delle colture (Liu et al., 2004; Wu et al., 2007). In campo vegetale, tra le strategie ... -
Identificazione di C-Numb come marcatore dell'ematopoiesi di Ciona intestinalis
(2014-03-25)In Metazoa the maintenance of individuality and the defense against pathogens is devolved to the molecular mechanisms of the innate immunity. Adaptive immunity complements innate immunity in gnathostome vertebrates, thus ... -
Identificazione e caratterizzazione di FoxP nel sistema nervoso centrale di Octopus vulgaris (Mollusca, Cephalopoda)
(2014-03-24)In this study, I searched and was able to identify FoxP in the transcriptome of the cephalopod mollusc Octopus vulgaris, an invertebrate. In addition, I attempted to analyze the expression of Ov-FoxP in the brain of this ... -
Il Recettore Estrogenico alfa e IRS-1 (Insulin Receptor Substate-1) come target dell’azione del Recettore Estrogenico beta
(2013-10-21)Estrogen signalling through ERα plays a central role in many diseases such as breast and endometrial cancer, osteoporosis and cardiovascular disease. In 1996 it has been discovered a second estrogen receptor in rat ... -
Il ruolo della Cromogranina A e dei suoi peptidi derivati, Serpinina e Catestatina, nella fisiopatologia cardiaca
(2012-11-24)Il ruolo cardiovascolare della CgA e dei suoi peptidi bioattivi è stato ampiamente documentato. I livelli plasmatici di CgA (range fisiologico da 0.5nM a 5nM), inizialmente utilizzati nella pratica clinica come biomarker ... -
<<Il>> ruolo del GPER nelle arterie uterine e mesenteriche in gravidanza
(2015-12-16)Low uteroplacental blood flow has been implicated as a cause of pregnancy hypertension and intrauterine fetal growth retardation. A successful pregnancy outcome requires a sufficient uteroplacental blood flow, which increases ... -
Impact of DNA methylation on plant growth and development: a study on a methylation-defective mutant of Arabidopsis thaliana
(2017-06-09)Epigenetic modifications of DNA contribute to chromatin remodeling process and gene expression regulation playing a relevant role on the development of eukaryotic organisms. DNA methylation is an important epigenetic mark ... -
Impact of DNA methylation status on plant response to cd explored through a transcriptomic analysis
(2019-04-11)Due to their sessile life style, plants are continuously exposed to a variety of abiotic and biotic stresses which could potentially hinder their growth, development, productivity and survival. In this scenario, it appears ...