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<<The>> estrogen receptor α is the key regulator of the bifunctional role of FoxO3a transcription factor in breast cancer motility and invasiveness
(2013-12-02)
The role of the Forkhead box class O (FoxO)3a transcription factor in breast
cancer migration and invasion is controversial. Here we show that FoxO3a
overexpression decreases motility, invasiveness, and anchorage-indep ...
Novel molecular mechanisms involved in the stimulatory action of zinc in breast cancer
(2016-11-22)
Lo Zinco (Zn), minerale essenziale che regola diverse funzioni biologiche, è coinvolto nella
progressione del tumore mammario. In particolare, è stato dimostrato che in seguito all’attivazione
indotta dallo Zn di recettori ...
Leptin mediates hyperglycemia-induced angiogenic effects in retinal endothelial cells
(2015-06-18)
Hyperglycemia (HG)-activated cytokines and inflammatory factors have been implicated in ocular
neovascularization and diabetic retinopathy (DR). However, the effects of HG on the expression
and function of leptin in ...
Bisphenol A induces gene expression changes an proliferative effects through GPER in breast cancer celles and cancer-associated fibroblasts
(2012)
Bisphenol A (BPA) is the principal constituent of baby bottles, reusable water bottles,
metal cans, and plastic food containers. BPA exerts estrogen-like activity by interacting
with the classical estrogen receptors (ER ...