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Evidences that Progesterone Receptor B decreases Estrogen Receptor α gene expression through its interaction to a half-PRE site at Estrogen Receptor alfa gene promoter.

Zupo,Silvia; Andò,Sebastiano; Lanzino,Marilena; De Amicis,Francesca (2013-10-23)

Insulin Receptor Substrate 1 modulates the transcriptional activity and turnover of Androgen Receptor in breast cancer cells.

Garofalo,Cecilia; Andò,Sebastiano (2013-10-23)

Inhibitionof cyclin D1 expression by androgen receptor in breast cancer cells-identification of a novel androgen response element

Capparelli,Claudia; Sisci,Diego; Lanzino,Marilena (2013-10-23)

Ruolo del sistema endocannabinoide nei meccanismi di neuroprotezione da 17β-estradiolo in un modello sperimentale di ischemia cerebrale focale

Mazzei,Cinzia; Bagetta,Giacinto (2013-10-28)

In questo studio sono stati determinati i livelli endogeni dell’endocannabinoide finora meglio caratterizzato, anandamide (AEA) e l’attività degli enzimi responsabili, rispettivamente, della sua sintesi e degradazione, ...

Inhibition of estrogen-dependent cyclin D1 expression by androgen receptor in MCF-7 breast cancer cell

Casaburi, Ivan; Andò, Sebastiano (2007-11-30)

PPARγ ligands as novel agents able to inhibit breast tumor growth and progression

Vizza, Donatella; Sisci, Diego; Bonofiglio, Daniela (2011)

Molecular Mechanisms of FXR-mediated Growth Inhibition in Hormone-dependent Cancers

Panza, Salvatore; Sisci, Diego; Catalano, Stefania (2011)

<<The>> estrogen receptor α is the key regulator of the bifunctional role of FoxO3a transcription factor in breast cancer motility and invasiveness

Cesario, Maria Grazia; Sisci, Diego (2013-12-02)

The role of the Forkhead box class O (FoxO)3a transcription factor in breast cancer migration and invasion is controversial. Here we show that FoxO3a overexpression decreases motility, invasiveness, and anchorage-indep ...

Estrogen Receptor beta, through Sp1, recruits a corepressor complex to the Estrogen Receptor alpha gene promoter in breast cancer cells

Zito, Domenico; Sisci, Diego; Andò, Sebastiano (2012)

Human Estrogen receptors alpha (α) and beta (β) are essential components of a complex signal transduction pathway that regulates mammary growth and development. Several studies have reported that normal breast tissues ...

DAX-1 at the connection between Androgen Receptor and Aromatase: a novel mechanism in the inhibition of estrogen-dependent cancer cell proliferation

Maris, Pamela; Sisci, Diego; Lanzino, Marilena (2012)