• Diagnostic challenges for genetic approaches in Amyotrophic Lateral Sclerosis 

  Perrone, Benedetta; Catalano, Stefania; Conforti, Francesca Luisa (Università della Calabria, 2023-02-28)

  Over the past years, our understanding of the genetic mechanisms involved in complex diseases, such as Amyotrophic Lateral Sclerosis, has increased dramatically. ALS is a fatal and devastating motor neuron disease for which ...

• Breast tumor microenvironment and endocrine resistance: dissecting the molecular link 

  Caruso, Amanda; Catalano, Stefania; Andò, Sebastiano (Università della Calabria, 2023-07-04)

• Small molecules from cycloaddition reactions: synthesis, theoretical perspectives, and biological evaluation 

  Tallarida, Matteo Antonio; Maiuolo, Loredana; Catalano, Stefania; Breugst, Martin; Rutjes, Floris (Università della Calabria, 2023-02-07)

  The research work is related to a Ph.D. course in Translational Medicine of the Department of Pharmacy, Health, and Nutritional Sciences, University of Calabria. The project was carried out at the Department of Chemistry ...

• New strategies in the design of functional and bioinspired materials for therapeutic applications 

  Servidio, Camilla; Andò, Sebastiano; Cassano, Roberta; Iemma, Francesca; Stellacci, Francesco (Università della Calabria, 2022-01-27)

• Design and development of new functional materials for pharmaceutical and biomedical purposes 

  Curcio, Federica; Andò, Sebastiano; Trombino, Sonia (Università della Calabria, 2022-02-15)

• Estrogen Related Receptor α (ERRα): a new target linking metabolism to Adrenocortical cancer progression 

  Nocito, Marta Claudia (Università della Calabria, 2022-06-14)

  I Carcinomi surrenalici (ACC) sono tumori rari e altamente aggressivi, associati a una prognosi infausta per un alto rischio di recidiva e di opzioni terapeutiche limitate [Stojadinovic A. et al., 2002]. Ad oggi sono stati ...

• Contribution of flavonoids and iridoids to health properties of edible plants of Arbutas, Cornas, and Vuccinium genera from Mediterranean area 

  Tenuta, Maria Concetta; Tundis, Rosa; Andò, Sebastiano; Deguin, Brigitte; Lallemand, Marie-Christine (Università della Calabria, 2020-06-19)

  Aim of the study: Natural compounds produced by the “nature laboratory” continue to play a leading role in the process of discovering and developing of new drugs, food supplements and/or functional foods. Today, in fact, ...

• Effect of bergamot essential oil and its constituent linalool on myogenic and neuronally-mediated contractions of human and rat isolated colon: potential benefits in complementary treatment of intestinal diseases 

  Straface, Marilisa; Andò, Sebastiano; Morrone, Luigi (Università della Calabria, 2020-07-01)

  Introduction Bergamot essential oil (BEO) is used in aromatherapy and as an additive to food and drink to promote a citrus flavour. In animal models, BEO can modulate the synaptic functions within the Central Nervous ...

• Evaluation of a PH-sensitive mesoporous silca -based nanosystem as a vehicle for targetedcancer therapy 

  Nigro, Alessandra; Andò, Sebastiano; Sisci, Diego (Università della Calabria, 2020-04-17)

• Advanced and smart nanocarriers for pharmaceutical applications 

  Mazzotta, Elisabetta; Andò, Sebastiano; Muzzalupo, Rita (Università della Calabria, 2020-04-17)

  The application of nanotechnology in drug formulation has made significant headway over the last decade. Nanoscale controlled release systems allow to revalue and reformulate old drugs through targeted delivery to the ...

• New perspective for the use of citrus by-productus in food and nutraceutical industries 

  Leporini, Mariarosaria; Andò, Sebastiano; Loizzo, Monica Rosa (Università della Calabria, 2020-07-06)

  Aim of the study: Citrus is the most produced tree fruit crop in the world. Almost 33% of the Citrus fruits are industrially processed for juice production, however, a great amount of Citrus wastes including peels, segment ...

• Synthetic strategies towards short-chain peptides for potential biomedical applications and tumor-targeted mesoporous silica-based drug delivery systems development 

  Comandè, Alessandra; Andò, Sebastiano; Leggio, Antonella (Università della Calabria, 2020-04-17)

  My PhD research project was focused on the design and development of short-chain peptides with biomedical applications and on the identification of new peptide synthesis strategies. Briefly, the specific objectives of my ...

• Novel insight into the protective role of androgen receptor in ER-positive breast cancer 

  Chiodo, Chiara; Andò, Sebastiano; Lanzino, Marilena (Università della Calabria, 2020-04-17)

  Introduction: Androgen receptor (AR) role in breast cancer appears to be clinically relevant and disease context specific. In estrogen receptor (ER) α-positive primary breast cancers, AR positivity correlates with low tumor ...

• Chemical modifications of polyphenols for the development of new molecules foods for the treatment of metabolic disorders 

  Carullo, Gabriele; Andò, Sebastiano; Aiello, Francesca (Università della Calabria, 2020-07-01)

  Metabolic disorders represent the principal cause of death in the industrialized world, affecting several people, because of their incorrect lifestyle. Among them, Type 2 Diabetes Mellitus and related comorbidities, such ...

• Advanced functionalized materials for multipurpose applications 

  Pantuso, Elvira; Andò, Sebastiano; Nicoletta, Fiore (Università della Calabria, 2021-03-21)

• Sistemi polimerici multicomponente per la veicolazione di principi attivi 

  Farfalla, Annafranca; Andò, Sebastiano; Iemma, Francesca (Università della Calabria, 2021-02-25)

  L’attività di ricerca riportata nel presente lavoro di tesi di dottorato si inserisce nel contesto della sintesi e caratterizzazione di materiali multifunzionali per la veicolazione e il direzionamento di principi ...

• Evidence that ANG II/AGTR1 signaling stimulates aromatase activity, enhances local estrogen production involved in Glioblastoma cell growth and progression 

  Russo, umberto; Andò, Sebastiano; De Amicis, Francesca (Università della Calabria, 2021-04-01)

• Progesterone Receptor B disrupts the metabolic reprogramming in breast cancer cell lines producing death by blocking energy producing pathways, and p53 may be linked in this tumour suppressive-action 

  Santoro, Marta; Andò, Sebastiano; Aquila, Saveria (Università della Calabria, 2021-11-10)

  Il carcinoma mammario (BC) rappresenta la più comune causa di morte per neoplasia nella donna. Nonostante i progressi fatti nella diagnosi precoce e nella terapia, esso resta una delle forme tumorali con prognosi infausta. ...

• Application of computational methodologies toward the identification of novel therapeutics and photodegradation studies for the design of light-stable formulations 

  Occhiuzzi, Maria Antonietta; Andò, Sebastiano; Grande, Fedora; Iole, Giuseppina (Università della Calabria, 2021-06-10)

• Charatterization of store-operated calcium entry in the neuroimmune response evoked by ischemic preconditioning in mice subjected to middle cerebral artery occlusion 

  Frisina, Marialaura; Andò, Sebastiano; Amantea, Diana (Università della Calabria, 2021-06-10)

  Cerebral ischemia is one of the leading causes of death and long-term disability worldwide. Currently approved therapies for ischemic stroke are limited to reperfusion through mechanical recanalization and/or pharmacological ...

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