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Effects of erythropoietin and stem cell factor on normal and cancer cells: implication for supportive therapy in oncological patients
(2013-10-23)
The ability of erythropoietin (Epo) to promote the production of red cells is currently exploited to
treat chemotherapy-induced anemia. However, the expression of Epo receptor (EpoR) in a variety
of cancer cells suggests ...
Ruolo del sistema endocannabinoide nei meccanismi di neuroprotezione da 17β-estradiolo in un modello sperimentale di ischemia cerebrale focale
(2013-10-28)
In questo studio sono stati determinati i livelli endogeni dell’endocannabinoide finora
meglio caratterizzato, anandamide (AEA) e l’attività degli enzimi responsabili,
rispettivamente, della sua sintesi e degradazione, ...
Dynamic effects of retinoic acid and its isomers on cancer and physiology
(2010-11-23)
In the search for new cancer chemo-preventive compounds, hundreds of naturally
occurring molecules have been evaluated. Among these, antioxidants appear to be
very promising. In this contest, over the last decade retinoids, ...
Relevance of nuclear IRS-1 in breast cancer
(2013-10-23)
Insulin receptor substrate 1 (IRS-1), one of the major molecules transmitting signals
from the insulin and insulin-like growth factor 1 receptors, has been implicated in breast
cancer. Recently, data obtained in different ...
Caratterizzazione del profilo neurochimico, neuropatologico e neourofarmacologico di un modello sperimentale di glaucoma acuto
(2013-10-28)
Glaucoma is a leading cause of irreversibile blindness characterized by the progressive
loss of retinal ganglion cells (RGCs). Elevated intraocular pressure is a major risk factor for
glaucoma; however, medical therapies ...